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Kate Clifford Larson will appear at 7:30 p.m. Wednesday at the Columbus Museum of Art, 480 E. Broad St. Her son, then 19, had learned that he has schizophrenia, and the family became absorbed with his treatment and care. Larson pored through Kennedy family letters and documents and conducted interviews about the daughter who was lobotomized in 1941 at the age of 23. Larson had become drawn to the story upon reading Rosemary's 2005 obituary in the Boston Globe.