Five things you need to know today, and how to get people downtown, part 2

Good morning, Boston. Here are the five most important things you need to know to start your workday.  Epizyme shares soar 60%French drugmaker Ipsen SA, which four years ago moved its U.S. headquarters to Cambridge, is snapping up the beleaguered cancer firm Epizyme Inc. for $247 million, Rowan Walrath reports.GE's Culp to lead GE Aviation General Electric Co. is switching up the top leadership roles in its aviation unit — the only one of the three segments that will be left