Five things you need to know, and so many nonprofits

Good morning, Boston. For those of you with schoolchildren, welcome to the second day of school vacation week — are the kids bored yet? Here are the five things you need to know in local business news to start your busy Tuesday.Hannah Green reports that Lexington-based T2 Biosystems Inc. has laid off “substantially all of its employees," including its CEO, CFO and general counsel, though they will stay on part time for now. Creating a high-frequency, decarbonized regional commut