Sublingual Cyclobenzaprine Improves Sleep Issues, Fatigue in Fibromyalgia

Originally published by our sister publication Pain Medicine NewsBy Zoe CunliffeSALT LAKE CITY—In research presented at the American Academy of Pain Medicine annual PainConnect, investigators found clinically meaningful sleep-related benefits for sublingual cyclobenzaprine hydrochloride (CBP; Tonmya, Tonix), which the FDA approved in late 2025 for the treatmemt of fibromyalgia.The research finds that sublingual CBP not only has a stronger safety profile than prior fibromyalgia therapies, b