How is 'Dune: Part 2' different from the book?

With the release of Dune: Part Two, Denis Villeneuve has officially (and successfully!) translated the entirety of Frank Herbert's Dune to the screen.Just like with 2021's Dune, Dune: Part Two makes some major changes from its source material. Some of these carry over from the first film. For example, since we didn't see any of the storyline where Duke Leto (Oscar Isaac) pretends to think Lady Jessica (Rebecca Ferguson) is a traitor in Dune, we don't get any of the in-book fallout from that plot