White Matter Worries: A Problem for DTI?

A new preprint called "A systematic bias in DTI findings" could prove worrying for many neuroscientists. In the article, authors Farshid Sepehrband and colleagues of the University of Southern California argue that commonly-used measures of the brain's white matter integrity may be flawed.The technique in question, diffusion tensor imaging (DTI), uses an MRI scanner to measure the diffusion of water molecules at different points in the brain. In white matter, water diffusion is constrain