Shining light on orphan receptors

Light has been used for the first time to activate a receptor for which the compound binding and controlling it naturally is unknown, as reported in Nature Chemical Biology today. A team of scientists including Harald Janovjak, Assistant Professor at the Institute of Science and Technology Austria (IST Austria), Álvaro Inglés-Prieto, first author and postdoc in the Janovjak group, and Eva Reichhart, PhD student in the Janovjak group, using libraries and cells from the Medical Unive