Researchers Discover a Gut Microbe Metabolite That Supercharges Cancer Immunotherapy

A microbial metabolite called 3,4 dihydroxybenzoic acid, derived from dietary fiber, improved antitumor immunity in mice. A compound made by gut bacteria during the breakdown of dietary fiber may offer a way to strengthen cancer immunotherapy. In mouse studies, University of Michigan researchers turned that compound into an oral drug that helped T cells attack [...]