Protein complex prevents genome instability

An international collaboration between Osaka University and the Friedrich Miescher Institute for Biomedical Research (FMI) in Switzerland is investigating the repair process of a serious form of DNA damage that can lead to instability of genetic material and tumor formation. The researchers are studying the roles of groups of proteins that control the repair of double-stranded breaks (DSBs) in DNA that occur from internal or external sources, such as UV irradiation.