One-step tumor detection from dynamic morphology tracking on aptamer grafted surface

A team of researchers from the University of Texas at Arlington (UT-Arlington) in Texas, USA has demonstrated a novel cancer cell detection method based on real time cell behavior tracking on engineered surfaces. A synthetic RNA molecule is coated on chip surface to identify cancer cells. The otherwise "calm and quiet" cells on this surface show interesting dancing behavior when their membrane receptors are matched to the surface RNA molecules. The behavior is quantified using interesting image