New Method for Detecting Unwanted DNA Breaks in Human Cells

Researchers at the Harvard Medical School have developed a new method for detecting unwanted DNA breaks across the entire genome of human cells induced by the popular gene-editing tools called CRISPR-Cas RNA-guided nucleases. Members of the same team that first described these off-target effects in human cells describe their new platform, called GUIDE-seq (Genome-wide Unbiased […]
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