CRISPR/Cas9 used to mimic mitotic recombination to help map out genes

(Phys.org)—A small team of researchers with the University of California has developed a way to use CRISPR/Cas9 to mimic mitotic recombination in yeast cells leading to a new way to map out genes and by doing so, determine their functions. In their paper published in the journal Science, Meru Sadhu, Joshua Bloom, Laura Day and Leonid Kruglyak describe how they developed the technique, how they tested it and how the technique may be used going forward.