Conformational Changes of EF-G on the Ribosome During tRNA Translocation

New research from Yale University provides insights into the conformational space that EF-G samples on the ribosome and reveals that tRNA translocation on the ribosome is facilitated by a structural transition of EF-G from a compact to an elongated conformation, which can be prevented by the antibiotic dityromycin. The ribosome is the protein-making “factory” within […]
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