Caught in the act: 3-D structure of an RNA-modifying protein determined in action

The structure of a bacterial RNA-binding protein has been determined in the act of modifying a molecule of RNA—an achievement that provides researchers with a unique view of the protein's function in action and could lead to clues that would help in the fight against the development of antibiotic-resistant infections. A paper describing the findings by a team of Penn State University researchers is published in the current issue of the journal Science.