Reduced activity of a brain protein linked to post-traumatic stress disorder

People with post-traumatic stress disorder (PTSD) have reduced activity of the protein serum and glucocorticoid regulated kinase 1 (SGK1) in their prefrontal cortices, and experimentally reducing the protein's activity in rats leads to PTSD-like behavior, according to a new study. The study suggests that augmenting activity of SGK1 may be therapeutic in PTSD.