Form424B4

TABLE OF CONTENTS Filed Pursuant to Rule 424(b)(4) Registration No. 333-248941 PROSPECTUS 6,000,000 Shares ADC THERAPEUTICS SA Common Shares We are offering 6,000,000 common shares. The Selling Shareholders identified in this prospectus, which are entities affiliated with two members of our board of directors, are offering 900,000 common shares if and to the extent that the underwriters exercise their option to purchase additional common shares described below. We will not receive any of the pro