Secrets of human protein interactions unveiled by massive sequencing and coevolution

(Centro Nacional de Investigaciones Oncológicas (CNIO)) Cells operate like an incredibly well-synchronized orchestra of interactions among proteins. Understanding this network is essential to determine the molecular mechanisms responsible for a multitude of diseases. In fact, it has been observed that protein interacting regions are preferentially mutated in tumors. A new study demonstrates that it is possible to understand a significant number of interactions among human proteins from th