Preventing of cardiac failure in the chronic phase

The onset of cardiac failure after acute myocardial infarction (AMI) is a serious problem throughout the world. Researchers have now clarified that the cell adhesion inhibition of periostin1 damages myocardinal cells, inducing compromised cardiac myocyte contractile force and myocytes death, leading to the onset of cardiac failure after AMI through the administration of periostin neutralizing antibodies they had developed on their own.