Preliminary: BRCA variations may work alongside COMT variation to reduce breast cancer

(George Washington University) George Washington University researchers, published in the New England Journal of Medicine, find through looking at genetic data sets of presumed cancer-free women who carry BRCA 1/2 variants, the co-occurrence of a rare COMT genetic variant in some women. This research outlines a strategy for looking at large genetic data sets for clues as to why a genetic carrier may never develop the associated diseases.