Natural metabolite can suppress inflammation

An international research team has revealed a substance produced in humans that can suppress the pro-inflammatory activity of macrophages -- specific immune cells. The substance known as itaconate is released in large quantities by macrophages themselves and according to the scientists, acts as an antioxidant and anti-inflammatory agent. These properties make itaconate promising for the treatment of such pathologies as cardiac ischemia, metabolic disorders and autoimmune diseases which may be as