Migraines May Begin Deep in the Brain

Blocking a single neurotransmitter in the brain may stop the firing of the nerves that are linked with migraine headaches, a new study in animals suggests. In experiments, researchers looked at the effects of two vasodilators — which are medicines that cause blood vessels to widen, increasing blood flow — on certain receptors in rats' brain cells. They found that when they administered one of these vasodilators, nicknamed PACAP, directly into the rats' brains, a cluster of neurons in