Brain Circuit Linked to Depression Found in Rats

The brain circuits responsible for the inability to feel pleasure have now been discovered in rats, a finding that could help researchers better understand the mechanisms underlying depression and schizophrenia. Previous brain-imaging research suggested that anhedonia might be linked to a part of the brain that sits just behind the forehead known as the medial prefrontal cortex. Now, scientists have conducted experiments on the medial prefrontal cortex of rats.