Universal Flu Vaccine Candidate Effective in Mice

University of Pennsylvania (UPenn) researchers hope to start clinical trials of a universal mRNA flu vaccine within the next two years, on the back of promising results from tests in multiple animal models. Unlike traditional vaccines that need to be reformulated every year to match mutated viral proteins and different viral strains, the new lipid nanoparticle (LNP)-encapsulated mRNA vaccine triggers strong antibody responses to a part of the viral hemagglutinin (HA) protein that doesn’t m