T-Cell Enzyme Uses Deadly Multipronged Attack on Bacteria

Researchers have discovered how an enzyme produced by immune system cells carries out a deadly, multipronged attack on invading bacteria. The enzyme, granzyme B, is released by cytotoxic T cells as part of the body’s natural fight against intracellular microbes. Collaborators at the University of Michigan and at Harvard University have now found that, unlike antibiotics, which disrupt a single bacterial process, granzyme B impacts on multiple bacterial processes all at the same time. The f