Study Suggests Novel Approach to Osteoarthritis Therapy

Scientists at The Scripps Research Institute (TSRI) report why the risk of osteoarthritis increases as we age. They also describe a new approach for developing new therapies to maintain healthy joints.The study (“ FoxO transcription factors modulate autophagy and proteoglycan 4 in cartilage homeostasis and osteoarthritis ”), which appears in Science Translational Medicine, suggests that FOXO proteins are responsible for the maintenance of healthy cells in the cartilage of our joints.