Study Suggests Molecular Switches, Plus Genes, Shape Role of Genetic Variation in Disease Risk

Clues to the contribution of genetic variation to disease risk lie not only in the genes, but also in the molecular switches that control those genes, according to a study published today.The study suggested that the effects of genetic variation on immune response are often hidden if not searched for thoroughly. The results, published in Nature Genetics , showed for the first time how immune cells created from human induced pluripotent stem cells (iPSCs) can model immune response variation betwe