Stem Cells in Body Transcriptionally Distinct from Those Extracted for Study

“Not just the FACS, ma’am, not just the FACS.” These words could have come from investigators who have applied a new technique to assess gene expression in stem cells. FACS, or fluorescence-activated cell sorting, is used to remove cells from their native environment and purify them for analysis. Another, newer technique, however, may better reflect stem cells’ in vivo state.The new technique, which labels newly transcribed RNA in vivo , has been applied by scientists bas