Small-Molecule RNA-Targeting Technology Kills Cancer Cells

Scientists at The Scripps Research Institute have developed a small molecule-based RNA editing tool that can selectively delete RNA targets associated with diseases such as cancer. Offering a potential alternative to CRISPR-Cas9 -based tools that edit DNA, the new technology, developed by Matthew D. Disney, Ph.D., attaches an RNA-targeting drug-like molecule to an RNA-degrading enzyme.Because the technology uses small molecules rather than proteins, it could also feasibly be packaged into a conv