Single-Cell Analysis for a Penny a Profile

Partitioning is expensive, but barcoding is cheap—that’s the idea behind a new technique for single-cell analysis. By dispensing with fancy cell sorters, custom microfluidics, and microwells, and introducing budget-friendly combinatorial barcoding, this new technique promises to democratize single-cell transcriptomics.The new technique, which is called split pool ligation-based transcriptome sequencing (SPLit-seq), was developed by scientists at the Allen Institute and the University