Signaling Protein Found That Can Act as Tumor Suppressor or Cancer Promoter

Scientists at the University of California San Diego School of Medicine and Moores Cancer Center report that a signaling protein that normally suppresses tumors can be manipulated (or re-programmed) by growth factors, turning it into a driver of malignant growth and metastasis. They published their study (“ Convergence of Wnt, growth factor, and heterotrimeric G protein signals on the guanine nucleotide exchange factor Daple ”) in Science Signaling.“Cellular prolifera