Shields Up for New Cancer Gene-Therapy Virus

The promise of gene therapy to treat cancer has always been limited by the vector used to deliver the rectified genetic payload. While off-targeting has always been a major concern, no less of an issue is the host immune system destroying the therapeutic virus before it has had a chance to complete its mission. Now, investigators at the University of Zurich (UZH) have developed a vector they believe will dramatically increase the efficiency of cancer gene therapy using human adenovirus 5. The fi