Scientists Link 200 Noncoding Mutations with Genes That Drive Different Cancers

Scientists in the U.S. have identified nearly 200 mutations in noncoding DNA that play functional roles in different cancers. Most of the somatic expression quantitative trait loci (eQTLs) appear to impact on a set of core pathways, which makes it possible to classify tumors into pathways-based subtypes, suggest the researchers at the University of California, San Diego (UCSD) and Stanford University School of Medicine.“Most cancer-related mutations occur in regions of the genome outside o