Sangamo Genome Editing Trial, Assessing MPS II Candidate, Treats First Patient

Sangamo Therapeutics said today it has treated the first patient in the Phase I/II CHAMPIONS clinical trial assessing its in vivo genome-editing candidate therapy SB-913 for mucopolysaccharidosis type II (MPS II), also called Hunter syndrome.“We are at the start of a new frontier of genomic medicine,” declared Sangamo CEO Sandy Macrae, M.B., Ch.B., Ph.D., in a statement. “For the first time, a patient has received a therapy intended to precisely edit the DNA of cells directly i