RUNX Proteins Found to be Integral to Efficient DNA Repair

Scientists from the Cancer Science Institute of Singapore (CSI Singapore) at the National University of Singapore report that RUNX proteins are integral to efficient DNA repair via the Fanconi Anemia (FA) pathway. The team undertook a thorough molecular characterization of RUNX proteins in the FA pathway that showed that the proteins had substantial physical association with DNA repair complexes and co-regulated the recruitment of DNA repair protein FANCD2 to sites of DNA damage.The finding