RNA-Based CRISPR Has Detailed Molecular Structure Revealed

Researchers at the Salk Institute have described for the first time the molecular structure of CRISPR-Cas13d, an enzyme for emerging RNA-editing technology. They were able to visualize the enzyme with cryo-electron microscopy (cryo-EM) as reported in an article (“ Structural Basis for the RNA-Guided Ribonuclease Activity of CRISPR-Cas13d ”) in  Cell .“CRISPR-Cas endonucleases directed against foreign nucleic acids mediate prokaryotic adaptive immunity and have been ta