Protein Linking Key Organelles May Shed Light on Neurodegenerative Disease Development

Scientists report that they have developed a technique to identify proteins that allow the mitochondria and the endoplasmic reticulum to attach to each other. Faulty connections between the ER and mitochondria have been implicated in several neurodegenerative diseases, including Alzheimer's, Parkinson's, and Huntington's diseases.The research ("Ascorbate Peroxidase Proximity Labeling Coupled with Biochemical Fractionation Identifies Promoters of Endoplasmic Reticulum Mitochondrial Cont