Poison Frogs Evolved Poison Resistance via Complementary Mutations

Brightly colored but capable of dark deeds, poison frogs have evolved several ways to accumulate toxic chemicals that are harmful to predators. For example, many poison frogs evolve resistance to their own toxins by swapping out amino acids in their neurotransmitter receptors. Thus, when modified, the receptors become less sensitive to the poison.Even more impressive, a new report indicates, some poison frogs have managed to retune a neurotransmitter receptor so that it is not only insensitive t