Pill May Replace Injection to Deliver Insulin, Other Peptide Drugs

It’s been the holy grail of drug delivery: a pill that can preserve the structural integrity of large, delicate proteins and peptides while carrying them past one forbidding barrier after another—the gastric acids of the gut, the protein-degrading enzymes of the intestine, the mucus layer of the intestine, and the tight junctions between the cells of the intestinal wall. Such a pill may soon be within the grasp of people with type 1 diabetes. This pill, which tucks insulin with an io