Parkinson's Disease Drug That Cools "Brains on Fire” Could Enter Human Trials in 2020

Researchers at the University of Queensland in Australia have identified a small molecule that can stop the progression of Parkinson’s disease (PD) and improve motor function in multiple mouse models. The team says human trials with an optimized compound could start within the next couple of years.The prototype molecule, MCC950, blocks an immune system target, the NLRP3 inflammasome, which the researchers' investigations showed is activated in the brains of PD patients and animal models. T