Pancreatic Cancer Prevented by "Super-Tumor Suppressor" Protein

Scientists have identified a "super-mutant" variant of the tumor suppressor protein p53, which boosts the transcription factor’s ability to prevent pancreatic cancer development in mice models. "It's not to say that mice with the mutated version of p53 would never get cancer, but this experiment suggests that this particular mutant is really potent in limiting tumor development," notes Stanford University School of Medicine’s Laura Attardi, Ph.D., professor of radiation oncology and