Novel Technique Opens Door to Super Resolution of Single Molecules in Cells

Researchers report that they have adapted a technique called DNA-PAINT to confocal microscopes to allow them to investigate molecules deep inside cells. They describe DNA-PAINT as a molecular imaging technology to localize fluorescent dyes.The team says it is now able to visualize a variety of different molecules, including combinations of different proteins, RNAs, and DNA throughout the entire depth of whole cells at high resolution. The study (“ Multiplexed 3D Super-Resolution