Noncoding RNA Drug Target for Colon Cancer Discovered
Long noncoding RNAs (lncRNAs) are, as the name suggests, long transcripts of RNA that do not code for proteins, but have been found to regulate a wide range of cell functions. Scientists at Case Western Reserve School of Medicine have now discovered that one lncRNA, designated lincDUSP, may play a role in initiating colon cancer and promoting disease progression, and so represent a novel target for drug development.The team found that lincDUSP was overexpressed in nearly every human colon cancer
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