New Protein Aggregation Tool Opens Door to Better Understanding of Neurodegenerative Diseases

Scientists from Boston University, MIT, and the Whitehead Institute for Biomedical Research, and others, say they have made a synthetic genetic tool named yTRAP (yeast Transcriptional Reporting of Aggregating Proteins) to quantitatively sense, measure, and manipulate protein aggregation in live cells. Their study (“A Genetic Tool to Track Protein Aggregates and Control Prion Inheritance”), published in  Cell , used yTRAP to research protein aggregates, including diseas