New Approach Combines Three Methods to Detect Structural Variants in Cancer Cells

Scientists say they have developed a new framework that can combine three existing methods of finding structural variants (SVs) within cancer cell DNA to learn more about how those cancers begin. The team published its study (“ Integrative detection and analysis of structural variation in cancer genomes ”) in Nature Genetics .“SVs can contribute to oncogenesis through a variety of mechanisms. Despite their importance, the identification of SVs in cancer genomes remain