New A2A Receptor Study Offers Insights on Memory Loss Associated with Aging

An international team says it has described a new mechanism involved in memory loss associated with aging. Their study (“ Age-related shift in LTD is dependent on neuronal adenosine A2A receptors interplay with mGluR5 and NMDA receptors ”), published in Molecular Psychiatry, shows that specific changes in the signaling of circuits involved in memory induce an abnormal response of the neurons in the brain that is associated with aging. Understanding these processes is crucia