Naturally Aged Mitochondria May Improve Study of Brain Aging

When the mitochondria within neurons age, they lose vigor, leaving the brain more vulnerable to age-related diseases and the ravages of aging generally. Yet well-aged mitochondria are usually hard to come by, at least in laboratory models, which tend to lose genetic markers of aging—at both the nuclear and mitochondrial levels. Unfortunately, mitochondria that have their markers of aging restored by artificial means, by chemical stresses, may lack all the subtleties of naturally aged mitoc