Mutations Making CRISPR Hyper-Accurate Discovered

The potential benefits of the CRISPR gene-editing system have been championed by a huge array of researchers, clinicians, and biotech companies. While the data in recent years supports that CRISPR/Cas9 is effective in altering genes to circumvent many disease states, the limitation of the system thus far has been the tendency of the Cas9 enzyme to cut at off-target sites. Now, investigators at the University of California, Berkeley, and Massachusetts General Hospital have identified a key region