Multiple Myeloma Patient Survival Associated with ADAR1 Enzyme Levels

Scientists at the University of California San Diego School of Medicine report that high ADAR1 enzyme levels correlate with reduced survival rates among patients with multiple myeloma. They also determined that blocking the enzyme reduces multiple myeloma regeneration in experimental models derived from patient cancer cells. The study (“ Alu-dependent RNA editing of GLI1 promotes malignant regeneration in multiple myeloma ”), published  in  Nature Communicati