Moving a Step Closer to Solving Problems of Autoimmune Disease and Transplant Rejection

Researchers at the Houston Methodist Research Institute report that they have identified a critical switch that controls T-cell function and dysfunction and have discovered a pathway to target it. Their study (“ Ablation of Transcription Factor IRF4 Promotes Transplant Acceptance by Driving Allogenic CD4 + T Cell Dysfunction ") appears in Immunity.According to Wenhao Chen, Ph.D., a scientist in the Immunobiology and Transplant Science Center at the Institute, what the team discov