Micropeptide Discovery May Lead to New Gene Therapy for Heart Failure

Scientists have discovered a micropeptide molecule that can restore normal heart function in mice, according to a study (“ The DWORF micropeptide enhances contractility and prevents heart failure in a mouse model of dilated cardiomyopathy ”) in  eLife . The micropeptide works by preventing calcium dysregulation and remodelling of the heart and could be a promising new gene therapy target to treat heart failure, say the researchers.“ Calcium (Ca 2+ ) dysregulation